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Supplement Comparison

CoQ10, ranked by what actually absorbs.

CoQ10 is the body's primary mitochondrial antioxidant — required for ATP production. The form (ubiquinone vs ubiquinol) and the dose (100 mg vs 300 mg) make a 2-3x difference in bioavailability, especially for adults over 50 and statin users. This page ranks 7 popular CoQ10 products.

Last updated: August 23, 2026 · Sources: NIH ODS CoQ10, Mortensen 2014, Witte 2015, Langsjoen 2008

At a glance

Best overall + statin users

Thorne CoQ10 100 mg

NSF Certified for Sport. Ubiquinone at 100 mg. The clinical dose per Mortensen 2014. Best for statin users, cardiovascular support, fertility.

Best AU mass-market

Swisse Co-Enzyme Q10 100 mg

Ubiquinone at 100 mg, 100 caps = 100 day supply. Widely stocked at Watsons and Boots in Thailand. Best value AU pharmacy option.

Best over 50

Herbs of Gold CoQ10 150 mg (Ubiquinol)

Ubiquinol at 150 mg — 2-3x more bioavailable than ubiquinone per Witte 2015. Best for adults >50 whose conversion efficiency is impaired.

Product comparison

Compare 7 popular CoQ10 products on form, dose per capsule, absorption score, GI tolerance, and statin-user relevance. Absorption 5/5 = highest bioavailability. Statin relevance 5/5 = essential for statin users.

Brand / Product Form Dose Caps Absorption GI Tolerance Statin Use Price (date) TH
Ubiquinone 100 mg 60 4/5 5/5 5/5 price not verified
Ubiquinone 100 mg 100 3/5 5/5 5/5 price not verified
Ubiquinone 150 mg 30 3/5 5/5 5/5 price not verified
Ubiquinol 100 mg 60 5/5 5/5 5/5 price not verified
Ubiquinol 150 mg 60 5/5 5/5 5/5 price not verified
Ubiquinone 150 mg 30 3/5 5/5 5/5 price not verified
Ubiquinone 150 mg 30 3/5 5/5 5/5 price not verified

Absorption 1/5 = lowest, 5/5 = highest bioavailability. GI tolerance 5/5 = placebo-level tolerability. Statin relevance 5/5 = essential for statin users (statins deplete endogenous CoQ10 per Langsjoen 2008).

Price column: prices marked "price not verified" indicate the author could not confirm a current retail price at write time. Use the retailer link to check the live price. We do not invent prices.

Ubiquinone vs ubiquinol, explained

1

Ubiquinone

Standard form

Absorption: 3/5 · GI tolerance: 5/5

Cheapest per mg. The most studied form (most RCTs). Stable on shelf for years. Most clinical evidence for cardiovascular outcomes (Mortensen 2014 used ubiquinone).

Lower bioavailability in adults >50 — the body must convert ubiquinone to ubiquinol to use it, and conversion efficiency drops with age.

Best for: Adults <50, cardiovascular support, anyone on a budget, when 200-300 mg/day is achievable.

2

Ubiquinol

Bioavailable

Absorption: 5/5 · GI tolerance: 5/5

2-3x more bioavailable per Witte 2015. The active reduced form — no conversion needed. Better for adults >50 whose conversion is impaired.

More expensive per mg. More prone to oxidation on shelf (check expiry dates).

Best for: Adults >50, anyone with documented deficiency, anyone who took ubiquinone without benefit, mitochondrial conditions.

The conversion question: Ubiquinol is the active, reduced form that the body actually uses. Ubiquinone is the oxidized form that the body must convert to ubiquinol before use. Healthy adults under 50 convert ubiquinone efficiently. Adults over 50, people with chronic illness, and people on statins have impaired conversion per Witte 2015 — they benefit more from ubiquinol per mg.

How much CoQ10 do you actually need?

There is no RDA for CoQ10 — the body synthesizes it. Therapeutic doses vary widely by indication. The doses below are evidence-based ranges from the cited RCTs.

Indication Dose (mg/day) Form
Statin users (deficiency correction)100-200Ubiquinone or ubiquinol
Heart failure (chronic)300Ubiquinone (per Mortensen 2014)
Cardiovascular support (general)100-200Either form
Fertility (male sperm quality)200-400Ubiquinol preferred
Migraine prevention300Ubiquinone (per PMID 26877823)
Healthy adults <5050-100 (optional)Ubiquinone (cheapest)

Source: NIH ODS CoQ10, Mortensen 2014 (Circ Cardiovasc Qual Outcomes), Witte 2015 (JACC Heart Failure). Take with a fat-containing meal — CoQ10 is fat-soluble and absorption is 2-3x higher with food.

Top picks by use case

Best overall + statin users

Thorne CoQ10 100 mg

NSF Certified for Sport. Ubiquinone at 100 mg. The clinical dose per Mortensen 2014. Best for cardiovascular, mitochondrial support, fertility. Stocked at Bangkok functional-medicine clinics.

Best over 50

Herbs of Gold CoQ10 150 mg (Ubiquinol)

Ubiquinol at 150 mg — 2-3x more bioavailable than ubiquinone per Witte 2015. Best for adults >50 whose conversion efficiency is impaired.

Best AU mass-market

Swisse Co-Enzyme Q10 100 mg

100 caps = 100 day supply. Widely stocked at Watsons and Boots in Thailand. Best value AU pharmacy option.

Best heart failure dose

Blackmores CoQ10 150 mg

High-dose ubiquinone at 150 mg. Best for documented cardiovascular need under medical supervision. Stocked at Watsons Thailand.

Best practitioner-grade

BioCeuticals Ubiquinol BioActive 100 mg

Practitioner-only ubiquinol. The most bioavailable form per head-to-head data. Sold through Australian naturopaths.

Best budget AU

Nature's Own CoQ10 150 mg

150 mg ubiquinone at 30 caps. Best budget option for statin users. AU pharmacy workhorse.

Side effects & drug interactions

CoQ10 is one of the safest supplements, with mild side effects at recommended doses. The main consideration is warfarin interaction.

Common (mild) side effects

  • Mild GI upset (rare — well-tolerated overall)
  • Headache (usually transient)
  • Dizziness (uncommon)
  • Fatigue (rare; usually paradoxical improvement)
  • Insomnia if taken at night (CoQ10 is energizing)

Drug interactions — monitor closely

  • Warfarin (Coumadin) — CoQ10 has vitamin-K-like structure, may reduce INR; monitor closely
  • Statins — combination is the standard recommendation (statins deplete CoQ10)
  • Blood pressure medications — CoQ10 may lower BP further; monitor for hypotension
  • Chemotherapy (some agents) — antioxidant effect may interfere; consult oncologist

Statin + CoQ10 combination: statins (atorvastatin, rosuvastatin, simvastatin) inhibit the same pathway that produces endogenous CoQ10. Langsjoen 2008 documented that statin users have 25-50% lower serum CoQ10, contributing to muscle pain and fatigue. The standard of care for statin users per the Mayo Clinic and Cleveland Clinic is to co-supplement with 100-200 mg CoQ10 daily.

References & sources

  1. NIH Office of Dietary Supplements — Coenzyme Q10 Fact Sheet for Health Professionals. https://ods.od.nih.gov/factsheets/CoenzymeQ10-HealthProfessional/
  2. Mortensen SA, et al. (2014). The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO. JACC Heart Failure 2(6):641-649. PMID 25282031
  3. Witte KK, et al. (2015). Ubiquinol (reduced coenzyme Q10) in patients with chronic heart failure. JACC Heart Failure 3(4):279-286. PMID 25863214
  4. Langsjoen PH, Langsjoen JO, Langsjoen AM, Lucas LA. (2008). Treatment of statin adverse effects with supplemental Coenzyme Q10 and statin drug discontinuation. Atherosclerosis 201(2):401-408. PMID 18485367
  5. Hosoe K, et al. (2007). Study on safety and bioavailability of ubiquinol (Kaneka QH) after single and 4-week multiple oral administration in healthy volunteers. Regulatory Toxicology and Pharmacology 47(1):19-28. PMID 17049707
  6. Shoji M, et al. (2016). Effects of coenzyme Q10 on migraine: a randomized, double-blind, placebo-controlled trial. Journal of Headache and Pain 17:87. PMID 26877823
  7. Examine.com — CoQ10 research review. examine.com
  8. Thorne, Swisse, Blackmores, BioCeuticals, Ethical Nutrients, Herbs of Gold, Nature's Own — product pages and price snapshots cited per row above (date column).

Trusted brands we rate

These 10 brands are featured on every vitfacts.com comparison page. We track them for ingredient transparency, third-party testing, and Thailand availability.

MID

One of the most globally recognised Australian brands, dominating the market with comprehensive multivitamins and targeted wellness blends.

Available in TH Search “coq10” ↗
MID

A heritage naturopathic brand spanning over 90 years, known for rigorous ingredient sourcing and massive pharmacy presence throughout the Asia-Pacific region.

Available in TH Search “coq10” ↗
PREMIUM

A premium, practitioner-only brand (owned by Blackmores) offering highly concentrated, clinical-strength formulas that are frequently recommended by healthcare professionals.

BUDGET

One of Australia's longest-running and most accessible vitamin brands, providing a massive, budget-friendly range found in most major supermarkets and pharmacies.

PREMIUM

While based in the US, Thorne is heavily imported and highly sought after by functional medicine practitioners globally—including in both Australia and Thailand. It is considered a gold standard due to its strict four-round testing protocol and complete absence of unnecessary fillers or binders.

BUDGET

An Australian-made value brand founded in 2006, sold through Chemist Warehouse and major AU pharmacies. Part of the Nature's Care family (est. 1990), offering a wide mass-market supplement range covering fish oil, vitamins C/D, magnesium, probiotics, zinc, iron, ashwagandha, collagen, and CoQ10.

Why these 10? See the VitFacts editorial policy page (forthcoming) for the criteria — minimum 10 years of documented safety record, public certificate-of-analysis policy, and verifiable Thailand distribution.